Cyclobenzaprine StatPearls NCBI Bookshelf

This pain-blocking mechanism can contribute to abuse of the medication and may result in Flexeril addiction. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

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Aftercare – Aftercare was created because many people often need more support once they have completed substance use treatment. Delphi’s Aftercare program gives you your own support network that understands what you’ve been through. It also offers you help with any other needs you may have, like housing, legal, and financial. The more common side effects of acetaminophen can include nausea and upset stomach. Benzodiazepines are sedatives that can help relax muscles.

Signs of a Cyclobenzaprine Overdose

Do not stand or sit up quickly, especially if you are an older patient. However, the half-life of immediate-release cyclobenzaprine is 18 hours on average, with a range of 8-37 hours. The extended-release form typically has a half-life of hours. If you miss a dose of this medicine, take it as soon as possible.

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Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations. Muscle relaxers like cyclobenzaprine usually last around four to six hours. Cyclobenzaprine has a half-life that ranges between eight to 37 hours for most adults.

Examples of drugs that can cause interactions with cyclobenzaprine are listed below. While the addictiveness of cyclobenzaprine is being debated, anyone exhibiting problematic patterns of substance use can benefit from addiction treatment. This is especially true if someone has been engaging in polydrug use with cyclobenzaprine and other substances.

How long does it take for cyclobenzaprine to work?

The Drug Abuse Warning Network (DAWN) published that in 2011, more than 11,000 people sought emergency department (ED) treatment for abuse of cyclobenzaprine. A drug overdose occurs when a toxin is unable to be successfully metabolized and removed from the body, and certain bodily functions are negatively affected. In the case of cyclobenzaprine, the Journal of Occupational Medicine and Toxicology reports that more than 100 mg of the drug taken in one dose can cause a toxic overdose. Dependence on cyclobenzaprine is recognized by the onset of withdrawal symptoms when the drug leaves the bloodstream.

• Elderly patients seem to tolerate cyclobenzaprine less and may develop hallucinations as well as significant anticholinergic side effects, such as sedation.
• While you are in detox, you may be given other medications to ease the withdrawal symptoms and perhaps, fluids to help keep you hydrated.
• Taking more may result in adverse Flexeril side effects or overdose.
• Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function.

If you are not able to swallow the extended-release capsule whole, mix the contents of the capsule with applesauce. After you eat the mixture, take a drink, and swish and swallow to make sure that you have received all the medication. We may receive advertising fees if you follow links to promoted online therapy websites. Join the thousands of people that have called a treatment provider for rehab information. Since overdosage is often deliberate, patients may attempt suicide by other means during the recovery phase.

They work by increasing the effects of certain neurotransmitters, which are chemicals that relay messages between your brain cells. Muscle spasticity, on the other hand, is a continuous muscle spasm that causes stiffness, rigidity, or tightness that can interfere with normal walking, talking, or movement. A long-acting formulation of cyclobenzaprine has been introduced and is believed by some clinicians to have a lower side effect profile than the immediate-release formulation of this drug. Cyclobenzaprine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works.

It is structurally similar to the tricyclic antidepressants and adverse effects similar to those seen with the tricyclic antidepressants are therefore to be expected. Although all skeletal muscle relaxants should be used with caution in older patients, diazepam especially should be avoided in older patients how long does it take flexeril to wear off or in patients with significant cognitive or hepatic impairment. Cyclobenzaprine can increase the effects of CNS depressants, such as alcohol, opioids, allergy medications, and sleeping pills. This enables the provider to evaluate for any potential interactions and helps them keep the patient safe.

It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Cyclobenzaprine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others. Yes, cyclobenzaprine can make you very sleepy and this side effect may get worse with higher doses.